The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2006
Filed:
Feb. 14, 2002
Marcel P. M. Van Aar, Weesp, NL;
Stefanus J. Schouten, Weesp, NL;
Jan Zorgdrager, Weesp, NL;
Michiel C. Heslinga, Weesp, NL;
Marcel P. M. van Aar, Weesp, NL;
Stefanus J. Schouten, Weesp, NL;
Jan Zorgdrager, Weesp, NL;
Michiel C. Heslinga, Weesp, NL;
Solvay Pharmaceuticals B.V., Weesp, NL;
Abstract
The invention relates to the mesylates of a group of piperazine derivatives and to a process for the preparation of these mesylates in an economic way in the high yield and of high purity. According to the process of the invention the synthesis of the piperazine ring and the mesylate formation are combined in a single reaction step. The invention relates to the mesylate of compounds of the formula (I) wherein X is a bicyclic heterocyclic phenyl group and Y is methyl, ethyl (optionally substituted with fluorine), cycloalkyl (3–7C) methyl, benzyl or m-phenyl benzyl