The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2006

Filed:

Nov. 29, 1999
Applicants:

Robert E. Reiter, Los Angeles, CA (US);

Owen N. Witte, Sherman Oaks, CA (US);

Charles L. Sawyers, Los Angeles, CA (US);

Inventors:

Robert E. Reiter, Los Angeles, CA (US);

Owen N. Witte, Sherman Oaks, CA (US);

Charles L. Sawyers, Los Angeles, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12P 21/06 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a human E25a protein which is upregulated in cancerous cells, including those of hormone refractory prostate cancer, colon cancer, breast cancer or other cancers of epithelial origin. The invention also provides nucleic acid molecules encoding E25a protein, nucleic acid probes which hybridize with nucleic acid molecules encoding E25a protein, and antibodies which bind E25a protein. E25a protein and its related molecules can be useful as diagnostic markers of cancer, including hormone refractory prostate cancer, and as specific therapeutic targets in this disease. The invention also provides methods for diagnosing cancer, including hormone refractory prostate cancer.


Find Patent Forward Citations

Loading…