The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2006
Filed:
Sep. 27, 2000
Waltraud Ankenbauer, Penzberg, DE;
Frank Laue, Paehl-Fischen, DE;
Harald Sobek, Penzberg, DE;
Michael Greif, Lenggries, DE;
Waltraud Ankenbauer, Penzberg, DE;
Frank Laue, Paehl-Fischen, DE;
Harald Sobek, Penzberg, DE;
Michael Greif, Lenggries, DE;
Roche Diagnostics GmbH, Mannheim, DE;
Roche Molecular Systems Inc., Alameda, CA (US);
Abstract
A purified thermostable enzyme is derived from the thermophilic archaebacterium. The enzyme can be native or recombinant, is stable under PCR conditions and exhibits double strand specific exonuclease activity. It is a 3'–5′ exonuclease and cleaves to produce 5′-mononucleotides. Thermostable exonucleases are useful in many recombinant DNA techniques, in combination with a thermostable DNA polymerase like Tag especially for nucleic acid amplification by the polymerase chain reaction (PCR).