The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2006
Filed:
May. 17, 2002
Karel J. Lambert, Woodinville, WA (US);
Panayiotis P. Constantinides, Bothell, WA (US);
Alexander K. Tustian, Bothell, WA (US);
Steven C. Quay, Edmonds, WA (US);
Karel J. Lambert, Woodinville, WA (US);
Panayiotis P. Constantinides, Bothell, WA (US);
Alexander K. Tustian, Bothell, WA (US);
Steven C. Quay, Edmonds, WA (US);
Sonus Pharmaceuticals, Inc., Bothell, WA (US);
Abstract
A method of making an emulsion of tocopherol incorporating a co-solvent and, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans by various routes, is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylated α-tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in emulsions of α-tocopherol.