The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2006
Filed:
Mar. 19, 2002
Wesley Peter Blackaby, Buckhurst Hill, GB;
Jose Luis Castro Pineiro, Bishops Stortford, GB;
Mark Stuart Chambers, Puckeridge, GB;
Simon Charles Goodacre, Benington, GB;
David James Hallett, Watford, GB;
Philip Jones, Pomezia, IT;
Richard Thomas Lewis, Bishops Stortford, GB;
Angus Murray Macleod, Bishops Stortford, GB;
Robert James Maxey, Amersham, GB;
Kevin William Moore, Buntingford, GB;
Leslie Joseph Street, Little Hallingbury, GB;
Wesley Peter Blackaby, Buckhurst Hill, GB;
Jose Luis Castro Pineiro, Bishops Stortford, GB;
Mark Stuart Chambers, Puckeridge, GB;
Simon Charles Goodacre, Benington, GB;
David James Hallett, Watford, GB;
Philip Jones, Pomezia, IT;
Richard Thomas Lewis, Bishops Stortford, GB;
Angus Murray MacLeod, Bishops Stortford, GB;
Robert James Maxey, Amersham, GB;
Kevin William Moore, Buntingford, GB;
Leslie Joseph Street, Little Hallingbury, GB;
Merck Sharp & Dohme Ltd., Hoddesdon, GB;
Abstract
A class of imidazo[1,2-α]pyrimidine derivatives, substituted at the 3-position by an optionally substituted five-membered or six-membered heteroaromatic ring, are selective ligands for GABAreceptors, in particular having good affinity for the α2 and/or α3 and/or α5 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.