The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2006
Filed:
Apr. 19, 2001
Applicants:
Maria Cristina Geroni, Milan, IT;
Paolo Cozzi, Milan, IT;
Italo Beria, Milan, IT;
Inventors:
Assignee:
Pharmacia Italia S.p.A., Milan, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4025 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compounds which are α-halogenoacryloyl distamycin derivatives of formula (I) wherein Ris a bromine or chlorine atom; Ris a distamycin or distamycin-like framework as set forth in the specification; or a pharmaceutically acceptable salt thereof; are cytotoxic agents particularly effective in the treatment of tumors over expressing GSH/GSTs system and which are poorly responsive or even resistant to conventional antitumor therapies.