The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2006
Filed:
Mar. 05, 2003
Richard Soltero, Holly Springs, NC (US);
Nnochiri N. Ekwuribe, Cary, NC (US);
Foyeke Opawale, Raleigh, NC (US);
Bruce Rehlaender, Chapel Hill, NC (US);
Anthony Hickey, Chapel Hill, NC (US);
LI LI Bovet, Chapel Hill, NC (US);
Richard Soltero, Holly Springs, NC (US);
Nnochiri N. Ekwuribe, Cary, NC (US);
Foyeke Opawale, Raleigh, NC (US);
Bruce Rehlaender, Chapel Hill, NC (US);
Anthony Hickey, Chapel Hill, NC (US);
Li Li Bovet, Chapel Hill, NC (US);
Nobex Corporation, Durham, NC (US);
Abstract
Pharmaceutical compositions that include a drug and/or drug-oligomer conjugate, a fatty acid component and a bile salt component, or a bile salt component without a fatty acid component are described. The drug can be covalently coupled to an oligomeric moiety. The fatty acid component and the bile salt component, when together, can be present in a weight-to-weight ratio of between 1:15 and 15:1 or any value between. Methods of treating diseases in a subject in need of such treatment using the pharmaceutical compositions of this invention are also provided, as well as methods of providing such pharmaceutical compositions.