The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2006

Filed:

Jan. 25, 2002
Applicants:

Min LI, Ringoes, NJ (US);

Robert S. Wu, West Orange, NJ (US);

Jane S. C. Tsai, Indianapolis, IN (US);

Inventors:

Min Li, Ringoes, NJ (US);

Robert S. Wu, West Orange, NJ (US);

Jane S. C. Tsai, Indianapolis, IN (US);

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/548 (2006.01); G01N 30/90 (2006.01); C07D 243/24 (2006.01);
U.S. Cl.
CPC ...
Abstract

A water-soluble reference standard is useful for immunoassays of a lipophilic drugs. The reference standard is a compound of formula (I):G-(L)—Y;  (I)where G is a lipophilic drug; L is a linker which is an alkyl group or heteroalkyl group containing from 1 to 20 carbon atoms; n is 0 or 1; and Y is a water-solubilizing group such as —SO, —NR—SO, —P(═O)(OH)(O), or —O—P(═O)(OH)(O); where R is H or an alkyl group of 1 to 10 carbon atoms.


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