The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2006
Filed:
Oct. 02, 1998
Jasper D. Rine, Moraga, CA (US);
Victor L. Boyartchuk, Berkeley, CA (US);
Matthew N. Ashby, Mill Valley, CA (US);
Jasper D. Rine, Moraga, CA (US);
Victor L. Boyartchuk, Berkeley, CA (US);
Matthew N. Ashby, Mill Valley, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Two genes which encode polypeptides that mediate post-prenylation processing steps in CAAX polypeptides such as Ras are provided. The two genes (AFC1 and RCE1) encode polypeptides that mediate the removal of the AAX tripeptide from the CAAX polypeptide following prenylation. The genes and encoded polypeptides provide assays for testing compounds for an effect on post-prenylation processing steps. A heat shock assay for assessing Ras activity is also provided.