The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2006

Filed:

Feb. 13, 2001
Applicants:

Kathleen A. Sullivan, Springfield, NJ (US);

Diana Benincasa, Elizabeth, NJ (US);

Margaret A. Cascieri, East Windsor, NJ (US);

Lyndon J. Mitnaul, Piscataway, NJ (US);

Lin-lin Shiao, Westfield, NJ (US);

Michael R. Tota, Middletown, NJ (US);

Inventors:

Kathleen A. Sullivan, Springfield, NJ (US);

Diana Benincasa, Elizabeth, NJ (US);

Margaret A. Cascieri, East Windsor, NJ (US);

Lyndon J. Mitnaul, Piscataway, NJ (US);

Lin-Lin Shiao, Westfield, NJ (US);

Michael R. Tota, Middletown, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/34 (2006.01); C12Q 1/00 (2006.01); C12N 5/00 (2006.01); C12N 15/02 (2006.01); C07H 19/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of identifying inhibitors of the fusion of two types of cells, particularly when fusion is mediated by the interaction of a viral protein and such cellular proteins as CD4 and chemokine receptors, are disclosed. The methods are suitable for identifying substances that are useful for the treatment and prevention of viral diseases. Particularly preferred methods are useful for the identification of inhibitors of HIV-1 infection.


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