The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2006
Filed:
Oct. 15, 2002
David E. Lanar, Takoma Park, MD (US);
Sheetij Dutta, Silver Spring, MD (US);
Lisa A. Ware, Silver Spring, MD (US);
Lalitha P. V. Nair, New Delhi, IN;
David E. Lanar, Takoma Park, MD (US);
Sheetij Dutta, Silver Spring, MD (US);
Lisa A. Ware, Silver Spring, MD (US);
Lalitha P. V. Nair, New Delhi, IN;
The United States of America as represented by the Secretary of the Army, Washington, DC (US);
Abstract
In this application is described the expression and purification of a recombinant(3D7) AMA-1 ectodomain. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant AMA-1 is useful as a diagnostic reagent, for use in antibody production, and as a protein for use alone, or as part of, a vaccine to prevent malaria.