The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2006

Filed:

Feb. 02, 1999
Applicants:

Jörg Reimann, Ulm-Lehr, DE;

Yechezkel Barenholz, Jerusalem, IL;

Dvorah Diminsky, Jerusalem, IL;

Reinhold Schirmbeck, Krumbach, DE;

Inventors:

Jörg Reimann, Ulm-Lehr, DE;

Yechezkel Barenholz, Jerusalem, IL;

Dvorah Diminsky, Jerusalem, IL;

Reinhold Schirmbeck, Krumbach, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/385 (2006.01); A61K 39/29 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions of HBsAg particles having biologically active molecules contained in the particles, and methods of their use, e.g. in stimulating enhanced immune responses, are described. Antigenic peptides contained in HBsAg particles were found to produce a CTL response where none was elicited by the peptide alone. Encapsulation of immunostimulating molecules, such as cytokines, greatly enhanced the CTL response evoked by the HBsAg particles themselves.


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