The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2006

Filed:

Oct. 20, 2003
Applicants:

Deana J. Dicosimo, Rockland, DE (US);

Hao NI, New Castle, DE (US);

Stephen K. Picataggio, Wilmington, DE (US);

John E. Seip, Alloway, NJ (US);

Rick W. YE, Hockessin, DE (US);

Tao Wang, Hockessin, DE (US);

Inventors:

Deana J. Dicosimo, Rockland, DE (US);

Hao Ni, New Castle, DE (US);

Stephen K. Picataggio, Wilmington, DE (US);

John E. Seip, Alloway, NJ (US);

Rick W. Ye, Hockessin, DE (US);

Tao Wang, Hockessin, DE (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Genes have been identified in thegenome that are responsive to various metabolic and growth conditions. The identified responsiveness of these genes allows for the use of their promoters in regulated gene expression in C1 metabolizing bacteria. In particular, the hps promoter, which in its native state drives the expression of 3-hexulose-6-phosphate synthase (HPS), was found to be useful for directing expression of heterolgous coding regions (e.g., crtZ) in the obligate methanotrophsp. 16a.


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