The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2006

Filed:

May. 03, 2004
Applicants:

David K. Ho, North Potomac, MD (US);

Raya Mandler, Bethesda, MD (US);

Ada Belinda Alvarado-lindner, Frederick, MD (US);

Kaye B. Dillah Upadhyay, Gaithersburg, MD (US);

David J. Newman, Wayne, PA (US);

Inventors:

David K. Ho, North Potomac, MD (US);

Raya Mandler, Bethesda, MD (US);

Ada Belinda Alvarado-Lindner, Frederick, MD (US);

Kaye B. Dillah Upadhyay, Gaithersburg, MD (US);

David J. Newman, Wayne, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 225/04 (2006.01); A61K 47/48 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to water-soluble drugs, compositions containing same, and, in particular, a water-soluble analogue of geldanamycin. This invention also relates to a method of producing water-soluble analogues of water-insoluble drugs through derivatization and conjugation with a polar moiety via a thiol ether bond with a heterobifunctional linking molecule.


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