The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2006
Filed:
Jul. 11, 2001
Haodong LI, Gaithersburg, MD (US);
Mark D. Adams, Cleveland Heights, OH (US);
Valérie Calenda, Strasbourg, FR;
Virginie Fataccioli, Thiais, FR;
Haodong Li, Gaithersburg, MD (US);
Mark D. Adams, Cleveland Heights, OH (US);
Valérie Calenda, Strasbourg, FR;
Virginie Fataccioli, Thiais, FR;
Human Genome Sciences, Inc., Rockville, MD (US);
Transgene S.A., Strasbourg, FR;
Abstract
The present invention relates to a human CTGF-2 polypeptide and DNA (RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques and antibodies and antagonist/inhibitors against such polypeptide. Also provided are methods of using the polypeptide therapeutically for stimulating angiogenesis enhancing the repair of connective and support tissue, promoting the attachment, fixation and stabilization of tissue implants and enhancing wound healing. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention are also disclosed.