The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2006
Filed:
Jul. 03, 2003
Yuanhao LI, Palo Alto, CA (US);
Deborah Farson, Belmont, CA (US);
Luqun Tao, Foster City, CA (US);
Dechao Yu, Foster City, CA (US);
Yuanhao Li, Palo Alto, CA (US);
Deborah Farson, Belmont, CA (US);
Luqun Tao, Foster City, CA (US);
DeChao Yu, Foster City, CA (US);
Cell Genesys, Inc., South San Francisco, CA (US);
Abstract
Adenovirus packaging cell lines for growth of an E1A/E1B deficient adenovirus that is substantially free of replication competent adenovirus (RCA) are provided. Methods for producing adenovirus substantially free of RCA are also provided, wherein the adenovirus is grown in a cell line containing coding sequences for adenovirus E1A and E1B, which are operably linked to promoters that lack polynucleotide sequences sharing substantial sequence identity with the native adenovirus E1A and E1B promoters.