The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2006

Filed:

Aug. 09, 2001
Applicants:

Michael J. Mahan, Santa Barbara, CA (US);

Douglas M. Heithoff, Goleta, CA (US);

David A. Low, Goleta, CA (US);

Robert L Sinsheimer, Santa Barbara, CA (US);

Inventors:

Michael J. Mahan, Santa Barbara, CA (US);

Douglas M. Heithoff, Goleta, CA (US);

David A. Low, Goleta, CA (US);

Robert L Sinsheimer, Santa Barbara, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

Bacteria and in particular pathogenic bacteria are treated in a manner which alters the bacteria's native level or activity of DNA methyltransferase (Dam). The alteration results in a change in the bacteria's native level of methylation of adenine in a GATC tetranucleotide which inhibits virulence of the bacteria. Thus, compounds which inhibit proliferation of bacteria are useful in treating bacterial infections.


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