The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2006
Filed:
Mar. 19, 1999
Frederic J. DE Sauvage, Foster City, CA (US);
Robert D. Klein, Palo Alto, CA (US);
Heidi S. Phillips, San Carlos, CA (US);
Arnon Rosenthal, Burlingame, CA (US);
Frederic J. de Sauvage, Foster City, CA (US);
Robert D. Klein, Palo Alto, CA (US);
Heidi S. Phillips, San Carlos, CA (US);
Arnon Rosenthal, Burlingame, CA (US);
Genentech, Inc., South San Francisco, CA (US);
Abstract
The present invention relates to nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, vectors and host cells expressing, and immunoadhesions and antibodies to mammalian GFRα3, a novel α-subunit receptor of the GDNF (i.e. GFR) receptor family. It further relates to an assay for measuring activation of an α-subunit receptor by detecting tyrosine kinase receptor activation (i.e., autophosphorylation) or other activities related to ligand-induced α-subunit receptor homo-dimerization or homo-oligomerization.