The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2006
Filed:
Oct. 05, 2001
Applicants:
Kwok-keung Tai, Santa Ana, CA (US);
Sylvie E. Blondelle, San Diego, CA (US);
Richard A. Houghten, Solana Beach, CA (US);
Mauricio Montal, La Jolla, CA (US);
Inventors:
Kwok-Keung Tai, Santa Ana, CA (US);
Sylvie E. Blondelle, San Diego, CA (US);
Richard A. Houghten, Solana Beach, CA (US);
Mauricio Montal, La Jolla, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 211/13 (2006.01); C07C 211/27 (2006.01); C07C 215/52 (2006.01); A61K 31/135 (2006.01);
U.S. Cl.
CPC ...
Abstract
Neuroprotectant agents are provided which do not contain peptides and axe protected from the degradation that limits the use of peptide-based drugs in systemic circulation. With great selectivity for NMDA receptors, the agents exert an open channel block on NMDA receptors, and protect neuronal cells containing such receptors from excitatoxic cell death.