The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 2006

Filed:

May. 16, 2002
Applicants:

William Brown, Montreal, CA;

Christopher Walpole, Montreal, CA;

Zhongyong Wei, Montreal, CA;

Inventors:

William Brown, Montreal, CA;

Christopher Walpole, Montreal, CA;

Zhongyong Wei, Montreal, CA;

Assignee:

AstraZeneca AB, Sodertalje, SE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); A61K 31/451 (2006.01); C07D 211/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of general formula I: Ris selected from any one of phenyl, pyridinyl, pyrrolyl, thienyl, furanyl, imidazolyl, triazolyl, thiazolyl and pyridine N-oxide; where each Rphenyl ring and Rheteroaromatic ring may optionally and independently be further substituted by 1, 2 or 3 substituents selected from straight and branched C–C?6? alkyl, NO, CF, C–Calkoxy, chloro, fluoro, bromo, and iodo. The substitutions on the phenyl ring and on the heteroaromatic ring may take place in any position on said ring systems; are disclosed and claimed in the present application, as well as salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain, anxiety and functional gastrointestinal disorders.


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