The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2006
Filed:
Jul. 22, 2004
Jeff Zablocki, Mountain View, CA (US);
Rao Kalla, Cupertino, CA (US);
Dewan Zeng, San Mateo, CA (US);
Jeff Zablocki, Mountain View, CA (US);
Rao Kalla, Cupertino, CA (US);
Dewan Zeng, San Mateo, CA (US);
CV Therapeutics, Inc., Palo Alto, CA (US);
Abstract
Disclosed are novel methods of antagonizing the Aadenosine receptor in a mammal, comprising administering to a mammal in need thereof a therapeutically effective dose of a compound of the formula:wherein Ris optionally substituted Calkyl; Y is Calkylene; and Z is phenyl that is optionally substituted with halo, hydroxy, amino, cyano, or optionally substituted Calkyl or a pharmaceutically acceptable salt, ester, or prodrug thereof. The Aadenosine receptors are antagonized in order to treat a disease state is chosen from renal failure, renal dysfunction, nephritis, hypertension, edema, Alzheimers disease, stress, depression, cardiac arrhythmia, restoration of cardiac function, congestive heart failure, diabetes, asthma, respiratory disorders, ischemia-induced injury of the brain, heart and kidney, and diarrhea.