The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2006
Filed:
Dec. 05, 2000
Michael Rosario Defelippis, Carmel, IN (US);
Michael Allen Dobbins, Lebanon, IN (US);
Alby David Sharknas, Indianapolis, IN (US);
Alex Mark Prokai, Carmel, IN (US);
Joseph Vincent Rinella, Ypsilanti, MI (US);
Michael Rosario DeFelippis, Carmel, IN (US);
Michael Allen Dobbins, Lebanon, IN (US);
Alby David Sharknas, Indianapolis, IN (US);
Alex Mark Prokai, Carmel, IN (US);
Joseph Vincent Rinella, Ypsilanti, MI (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
The present invention provides means to improve the chemical stability of aqueous, parenteral pharmaceutical compositions comprising a polypeptide and glycerin. Reactive aldehydes are identified in commercial glycerins, and means for reducing such are provided. Convenient means are provided to assay for reactive aldehydes in glycerin, and a strong linear correlation between the level of reactive aldehydes in glycerin and chemical stability of compositions comprising a polypeptide and glycerin is demonstrated. The invention includes aqueous compositions comprising a polypeptide and glycerin having improved chemical stability compared to compositions previously known.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile