The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2006
Filed:
Mar. 10, 2003
Applicants:
Walter Cabri, Rozzano, IT;
Paolo Paissoni, Druento, IT;
Jacopo Roletto, Turin, IT;
Piera Fonte, Turin, IT;
Sara Olmo, Turin, IT;
Inventors:
Walter Cabri, Rozzano, IT;
Paolo Paissoni, Druento, IT;
Jacopo Roletto, Turin, IT;
Piera Fonte, Turin, IT;
Sara Olmo, Turin, IT;
Assignee:
Antibioticos S.p.A., Rodano, IT;
Primary Examiner:
Int. Cl.
CPC ...
C07D 457/02 (2006.01); C07D 457/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for the synthesis of pergolide (Formula (I)) (D-6-n-propyl-8βmethylmercaptomethylergo line) from acid 9,10-dihydrolysergic is herein disclosed. The process can be carried out without isolating most intermediates and is particularly convenient both from the yield and safety standpoint. Moreover, pergolide thereby obtained is highly pure and can be conveniently transformed into pergolide mesylate