The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2006
Filed:
Feb. 04, 2000
Applicants:
Eberhard Hildt, Berlin, DE;
Peter Hofschneider, Munich, DE;
Inventors:
Eberhard Hildt, Berlin, DE;
Peter Hofschneider, Munich, DE;
Assignee:
Island Pharmaceuticals Ltd., Douglas, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to particles, comprising: a protein envelope with a fusion protein, which comprises a virus protein, a cell permeability-mediating peptide and a heterologous cell-specific binding site; and a nucleic acid present in the protein envelope, which comprises the sequence for a virus-specific packaging signal and a structural gene. The invention further relates to methods for the preparation of such particles and means suitable for this purpose, as well as the use of the particles in gene therapy.