The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2006

Filed:

Apr. 27, 2000
Applicants:

Ai-zhi Piao, Salt Lake City, UT (US);

Chung Shih, Sandy, UT (US);

Inventors:

Ai-Zhi Piao, Salt Lake City, UT (US);

Chung Shih, Sandy, UT (US);

Assignee:

Macromed, Inc., Sandy, UT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); A61F 13/00 (2006.01); A61K 9/48 (2006.01); A61K 9/20 (2006.01); A61K 9/22 (2006.01);
U.S. Cl.
CPC ...
Abstract

A water soluble, biodegradable reverse thermal gelation system comprising a mixture of at least two types of tri-block copolymer components is disclosed. The tri-block copolymer components are made of a hydrophobic biodegradable polyester A-polymer block and a hydrophilic polyethylene glycol B-polymer block. The drug release and gel matrix erosion rates of the biodegradable reverse thermal gelation system may be modulated by various parameters such as the hydrophobic/hydrophilic component contents, polymer block concentrations, molecular weights and gelation temperatures, and weight ratios of the tri-block copolymer components in the mixture.


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