The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2006
Filed:
Mar. 03, 2004
Ron L. Hale, Woodside, CA (US);
Joshua D. Rabinowitz, Mountain View, CA (US);
Dennis W. Solas, San Francisco, CA (US);
Alejandro C. Zaffaroni, Atherton, CA (US);
Ron L. Hale, Woodside, CA (US);
Joshua D. Rabinowitz, Mountain View, CA (US);
Dennis W. Solas, San Francisco, CA (US);
Alejandro C. Zaffaroni, Atherton, CA (US);
Alexza Pharmaceuticals, Inc., Palo Alto, CA (US);
Abstract
The present invention relates to the delivery of compounds for the treatment of migraine and headache through an inhalation route. Specifically, it relates to aerosols containing rizatriptan or zolmitriptan that are used in inhalation therapy. In a method aspect of the present invention, rizatriptan or zolmitriptan is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of rizatriptan or zolmitriptan on a solid support to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% drug degradation products. In a kit aspect of the present invention, a kit for delivering rizatriptan or zolmitriptan through an inhalation route is provided which comprises: a) a thin coating of a rizatriptan or zolmitriptan composition; and, b) a device for dispending said thin coating as a condensation aerosol.