The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2006
Filed:
Dec. 24, 1998
Eugene M. Johnson, St. Louis, MO (US);
Jeffrey D. Milbrandt, St. Louis, MO (US);
Paul T. Kotzbauer, Aston, PA (US);
Patricia A. Lampe, St. Louis, MO (US);
Robert Klein, Palo Alto, CA (US);
Fred Desauvage, Foster City, CA (US);
Eugene M. Johnson, St. Louis, MO (US);
Jeffrey D. Milbrandt, St. Louis, MO (US);
Paul T. Kotzbauer, Aston, PA (US);
Patricia A. Lampe, St. Louis, MO (US);
Robert Klein, Palo Alto, CA (US);
Fred DeSauvage, Foster City, CA (US);
Washington University, St. Louis, MO (US);
Abstract
A novel growth factor, persephin, which belongs to the GDNF/neurturin family of growth factors, is disclosed. The human, mouse and rat amino acid sequences have been identified. Human, mouse and rat persephin genomic DNA sequences have been cloned and sequenced and the respective cDNA sequences identified. In addition, methods for treating degenerative conditions using persephin, methods for detecting persephin gene alterations and methods for detecting and monitoring patient levels of persephin are provided. Methods for identifying additional members of the persephin-neurturin-GDNF family of growth factors are also provided.