The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2006
Filed:
Dec. 30, 1999
Eugene M. Johnson, St. Louis, MO (US);
Jeffrey D. Milbrandt, St. Louis, MO (US);
Paul T. Kotzbauer, Swarthmore, PA (US);
Patricia A. Lampe, St. Louis, MO (US);
Eugene M. Johnson, St. Louis, MO (US);
Jeffrey D. Milbrandt, St. Louis, MO (US);
Paul T. Kotzbauer, Swarthmore, PA (US);
Patricia A. Lampe, St. Louis, MO (US);
The National Institutes of Health, Bethesda, MD (US);
Abstract
A novel growth factor, neurturin, is disclosed and the human and mouse amino acid sequences are identified. Human and mouse neurturin genomic DNA sequences have been cloned and sequenced and the respective cDNA sequences identified. The subcloning into vectors and the preparation of cells stably transformed with the vectors are also disclosed. In addition, methods for treating degenerative conditions, tumor cells and obesity; methods for detecting gene alterations and methods for detecting and monitoring patient levels of neurturin are provided. Methods for identifying additional members of the neurturin-GDNF family of growth factors are also provided.