The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2006
Filed:
Feb. 20, 2003
Jian-min Fu, Kalamazoo, MI (US);
Jeffrey W. Corbett, Portage, MI (US);
Michael Dalton Ennis, Mattawan, MI (US);
Kristine E. Frank, Portage, MI (US);
Robert Louis Hoffman, Kalamazoo, MI (US);
Patrick R. Verhoest, Augusta, MI (US);
Jian-Min Fu, Kalamazoo, MI (US);
Jeffrey W. Corbett, Portage, MI (US);
Michael Dalton Ennis, Mattawan, MI (US);
Kristine E. Frank, Portage, MI (US);
Robert Louis Hoffman, Kalamazoo, MI (US);
Patrick R. Verhoest, Augusta, MI (US);
Pfizer Inc, New York, NY (US);
Abstract
This invention relates to substituted pyrimidinone and pyrimidithione derivatives that bind with high affifnity to CRF1 receptors, including human CRF1 receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety disorders, and depression and stress related disorders.