The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2006
Filed:
Jan. 13, 1999
Andreas Bergmann, Berlin, DE;
Joachim Struck, Berlin, DE;
Nils Morgenthaler, Berlin, DE;
Wolfgang Weglöhner, Berlin, DE;
Jörg-michael Hollidt, Berlin, DE;
Andreas Bergmann, Berlin, DE;
Joachim Struck, Berlin, DE;
Nils Morgenthaler, Berlin, DE;
Wolfgang Weglöhner, Berlin, DE;
Jörg-Michael Hollidt, Berlin, DE;
B.R.A.H.M.S Aktiengesellschaft, Hennigsdorf, DE;
Abstract
Improved receptor assays for the detection of thyroid stimulating hormone receptor (TSHR) autoantibodies are described which use immobilized, affinity-purified rTSHR preparations as specific binders. This format, as well as novel measures for neutralizing pathologically increased human TSH (hTSH) levels in the sera, e.g., by the addition of anti-hHSH antibody, and/or eliminating the influence of anti-bovine TSH antibody, result in increased assay reliability and open up the possibility of preparing the assay constituents in a ready to use and/or well-standardized form for automatic processing and/or convenient marketing.