The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2006
Filed:
May. 02, 2002
Martin Howard Infeld, Upper Montclair, NJ (US);
Wantanee Phuapradit, Clifton, NJ (US);
Navnit Hargovindas Shah, Clifton, NJ (US);
Lin Zhang, Piscataway, NJ (US);
Martin Howard Infeld, Upper Montclair, NJ (US);
Wantanee Phuapradit, Clifton, NJ (US);
Navnit Hargovindas Shah, Clifton, NJ (US);
Lin Zhang, Piscataway, NJ (US);
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
A solid unit oral pharmaceutical dosage form of amorphous nelfinavir mesylate is provided comprising amorphous nelfinavir mesylate in an amount of from about 400 mg to about 700 mg calculated as nelfinavir base, and a pharmaceutically acceptable water soluble, non-ionic synthetic block copolymer of ethylene oxide and propylene oxide, the copolymer having a melting point of at least about 45° C. and an HLB value at 25° C. of from about 18 to about 29, wherein the copolymer is present from about 40% to about 65% by weight of the nelfinavir mesylate. A hot melt granulation process for making the dosage form is provided.