The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2006
Filed:
Jul. 14, 2003
A. Dean Sherry, Dallas, TX (US);
Mark Woods, Dallas, TX (US);
Zoltan Kovacs, Lewisville, TX (US);
Board of Regents, The University of Texas System, Austin, TX (US);
Macrocyclics, Dallas, TX (US);
Abstract
The present invention is directed, in general, to a contrast agent comprising a tetraazacyclododecane ligand and comprising a macrocyclic ring and a paramagnetic metal ion coordinated to the tetraazacyclododecane ligand. Pendent arms R, R', R″ and R′″ attached to a ring nitrogen. The pendent arms have the general formula: −C′HRRand for three or more of the pendant arms a chirality of the carbon atoms C′ are identical for each of three or more of the pendant arms. The Rgroup is larger than hydrogen and Ris selected from the group consisting of: an alcohol, amides, a carboxylate, phosphinates and a phosphonate. One or more substituents Ris a group larger than a methyl group and is located on one or more ring carbons.