The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2006
Filed:
Sep. 24, 2001
Pamela T. Manning, Labadie, MO (US);
Jane R. Connor, University City, MO (US);
Karen Seibert, St. Louis, MO (US);
Chinthalapally V. Rao, Croton-on-Hudson, NY (US);
Bandaru S. Reddy, Suffern, NY (US);
Pamela T. Manning, Labadie, MO (US);
Jane R. Connor, University City, MO (US);
Karen Seibert, St. Louis, MO (US);
Chinthalapally V. Rao, Croton-on-Hudson, NY (US);
Bandaru S. Reddy, Suffern, NY (US);
Pharmacia Corporation, Chesterfield, MO (US);
Abstract
Agents and methods for chemoprevention and treatment of neoplasia are described, the agents including a selective inhibitor of inducible nitric oxide synthase and a combination of a selective inhibitor of inducible nitric oxide synthase and an inhibitor of cylcooxygenase-2 in a pharmaceutical composition. The agents and methods are used for chemoprevention and treatment of neoplasia including colorectal cancer and other cancers affecting epithelial cells throughout the body. The agents can also be used to treat the fibrosis that occurs with radiation therapy, as well as adenomatous polyps, including those with familial adenomatous polyposis (FAP).