The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2006

Filed:

Apr. 17, 2002
Applicants:

Manfred Watzele, Weilheim, DE;

Thomas Hoffmann, Neu-Edingen, DE;

Cordula Nemetz, Wolfratshausen, DE;

Dieter Heindl, Tutzing, DE;

Thomas Metzler, Munich, DE;

Wolfgang Mutter, Bernried, DE;

Inventors:

Manfred Watzele, Weilheim, DE;

Thomas Hoffmann, Neu-Edingen, DE;

Cordula Nemetz, Wolfratshausen, DE;

Dieter Heindl, Tutzing, DE;

Thomas Metzler, Munich, DE;

Wolfgang Mutter, Bernried, DE;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention concerns a method for improving the stability of linear short DNA towards exonucleases in cell-free in vitro transcription/translation systems using lysates containing exonucleases or in cellular systems containing exonucleases, wherein the stability of the linear short DNA is improved by adding unspecific linear DNA.


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