The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2006
Filed:
Jul. 17, 2002
Robert G. Chapman, Burlingame, CA (US);
Pejman Ghanouni, Menlo Park, CA (US);
Igor Shmulevich, San Ramon, CA (US);
David Balaban, San Jose, CA (US);
Joseph A. Heanue, Halfmoon Bay, CA (US);
Andrew P. May, San Francisco, CA (US);
Nikolai Sharkov, San Francisco, CA (US);
Robert G. Chapman, Burlingame, CA (US);
Pejman Ghanouni, Menlo Park, CA (US);
Igor Shmulevich, San Ramon, CA (US);
David Balaban, San Jose, CA (US);
Joseph A. Heanue, Halfmoon Bay, CA (US);
Andrew P. May, San Francisco, CA (US);
Nikolai Sharkov, San Francisco, CA (US);
MDS Sciex, South San Francisco, CA (US);
Abstract
Disclosed are methods for analyzing molecular binding events in which the formation of ligand/antiligand complexes can be directly detected in a mixture without requiring separation of the components of the mixture from each other by measuring bulk properties of the mixture (i.e., properties that have contributions from several or all of the components present in the mixture). Using these techniques, it is possible to screen libraries without labeling either the target antiligand or ligand. The invention also provides a method for determining the strength of ligand/antiligand binding by further analysis of the same signals.