The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2006
Filed:
May. 28, 2002
Applicants:
Michael J. Kuhar, Baltimore, MD (US);
Frank Ivy Carroll, Durham, NC (US);
John W. Boja, Baltimore, MD (US);
Anita H. Lewin, Chapel Hill, NC (US);
Philip Abraham, Cary, NC (US);
Inventors:
Michael J. Kuhar, Baltimore, MD (US);
Frank Ivy Carroll, Durham, NC (US);
John W. Boja, Baltimore, MD (US);
Anita H. Lewin, Chapel Hill, NC (US);
Philip Abraham, Cary, NC (US);
Assignee:
Research Triangle Institute, Research Triangle Park, NC (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); C07D 451/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
Tropane derivatives having a high binding affinity and selectivity for dopamine transporters bear, on the tropane backbone either a carboxylic ester or isoxazole moiety, as well as a substituted phenyl moiety. The compounds have utility both as pharmaceutical and as imaging agents, when one or more atoms are radioactive.