The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2006
Filed:
Jan. 15, 2003
Applicants:
Victor E. Marquez, Montgomery Village, MD (US);
Pamela L. Russ, Great Falls, VA (US);
Inventors:
Victor E. Marquez, Montgomery Village, MD (US);
Pamela L. Russ, Great Falls, VA (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/54 (2006.01); C07D 239/553 (2006.01); A61K 31/513 (2006.01); A61P 31/22 (2006.01);
U.S. Cl.
CPC ...
Abstract
The embodiments described herein concern 5-substituted pyrimidine derivatives of conformationally locked nucleoside analogues and to the use of these derivatives as anti-viral and anti-cancer agents. The compounds are of the formula:wherein B is uracil-1-yl or cytosin-1-yl having a 5-substituent selected from halogen, alkyl, alkenyl, and alkynyl, with the proviso that where B is uracil-1-yl, the 5-substituent is not methyl. The compounds are useful in the treatment of Herpes simplex virus (HSV).