The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2006
Filed:
Sep. 03, 1999
Joel Haynes, Newmarket, CA;
Michel Henri Klein, Willowdale, CA;
Benjamin Rovinski, Thornhill, CA;
Shi Xian Cao, Etobicoke, CA;
Joel Haynes, Newmarket, CA;
Michel Henri Klein, Willowdale, CA;
Benjamin Rovinski, Thornhill, CA;
Shi Xian Cao, Etobicoke, CA;
Aventis Pasteur Limited, Toronto, CA;
Abstract
The present invention is directed toward methods for the production of non-infectious, replication-deficient, immunogenic human immunodeficiency virus (HIV)-like particles. These particles are prepared from a recombinant expression vector comprising a heterologous promoter operatively connected to a DNA molecule comprising a modified HIV genome devoid of the long terminal repeat (LTR) regulatory regions but containing at least the gag and pol genes in their natural genomic arrangement. This vector is introduced into mammalian cells to produce the particles of interest. These particles should prove useful in a number of diagnostic, virologic, and immunologic applications.