The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2006
Filed:
Sep. 08, 2000
Arthur J. Coury, Boston, MA (US);
Stephen D. Goodrich, Norcross, GA (US);
Hildegard M. Kramer, Westport, CT (US);
Luis Z. Avila, Arlington, MA (US);
John F. Traverse, Somerville, MA (US);
Peter K. Jarrett, Sudbury, MA (US);
Arthur J. Coury, Boston, MA (US);
Stephen D. Goodrich, Norcross, GA (US);
Hildegard M. Kramer, Westport, CT (US);
Luis Z. Avila, Arlington, MA (US);
John F. Traverse, Somerville, MA (US);
Peter K. Jarrett, Sudbury, MA (US);
Genzyme Corporation, Cambridge, MA (US);
Abstract
Hydrogels intended for orthopedic applications, including repair and regeneration of cartilage, bone, joint surfaces and related tissues, must possess greater strength and toughness than hydrogels used in soft tissue repair. A hydrogel formulation is provided which has high strength, toughness, a suitable mechanical modulus and low equilibrium hydration. It may also have controlled porosity or degradation time. It can be made to polymerize in situ with high ('good' to 'excellent') adherence to target tissue or surfaces. A preferred formulation for forming such gels comprises 40 to 80% by weight of a low-molecular weight polar monomer and 30 to 10% of a hydrophilic macromeric crosslinker.