The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2006

Filed:

Aug. 27, 2003
Applicants:

Mark A. Dombroski, Waterford, CT (US);

Michael A. Letavic, Mystic, CT (US);

Kim F. Mcclure, Mystic, CT (US);

Inventors:

Mark A. Dombroski, Waterford, CT (US);

Michael A. Letavic, Mystic, CT (US);

Kim F. McClure, Mystic, CT (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/02 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel cycloalkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the present invention are potent inhibitors of MAP kinases, preferably p38 kinase. They are useful in the treatment of inflammation, osteoarthritis, rheumatoid arthritis, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.


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