The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2006

Filed:

Aug. 23, 2002
Applicants:

Jennifer V. Hines, Athens, OH (US);

Stephen C. Bergmeier, Athens, OH (US);

Tina M. Henkin, Dublin, OH (US);

Frank J. Grundy, Dublin, OH (US);

Inventors:

Jennifer V. Hines, Athens, OH (US);

Stephen C. Bergmeier, Athens, OH (US);

Tina M. Henkin, Dublin, OH (US);

Frank J. Grundy, Dublin, OH (US);

Assignee:

Ohio University, Athens, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/422 (2006.01); C07D 263/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds that are selective binding agents specific for RNA secondary and tertiary structures and a fluorescence assay for detecting the binding of small molecules to T-box antiterminator model mRNAs. The compounds include novel tri-substituted oxazolidinones and amino alcohols. The assay provides fluorescently labeled model mRNAs that include conserved sequence information typical of antiterminator bulge regions found in the mRNA of T-box gene regulatory systems.


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