The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7005139 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 28, 2006

Filed:

Apr. 05, 2001
Applicants:

Jeffrey Tze Fei Wong, Mid-levels, HK;

Shui Ying Tsang, Shatin, HK;

Inventors:

Jeffrey Tze Fei Wong, Mid-levels, HK;

Shui Ying Tsang, Shatin, HK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 48/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides compositions containing an effective amount of a therapeutic agent encapsulated in a liposome coupled to a desialyated glycoprotein, e.g., desialyated glycoprotein-α1. This invention further provides methods for the targeted delivery of a therapeutic agent to a tissue expressing asialoglycoprotein receptors by delivery to the tissue an effective amount of a composition containing an effective amount of the agent encapsulated in a liposome coupled to a desialyated glycoprotein, e.g., desialyated glycoprotein-α1. Also provided by this invention is a method for inhibiting the proliferation of liver cancer by administering to a subject in need of such therapy an effective amount of a composition containing doxorubicin encapsulated in desialyated glycoprotein-α1 coupled to a liposome.


Find Patent Forward Citations

Wong, Jeffrey Tze Fei. (2006). Compositions and methods for the targeted delivery of agents to treat liver cancer (U.S. Patent No. 7005139). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7005139

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