The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2006

Filed:

Sep. 23, 2002
Applicants:

Tony Giordano, Phoenixville, PA (US);

Michael A. Sturgess, Quakertown, PA (US);

Samala J. Rao, West Chester, PA (US);

Inventors:

Tony Giordano, Phoenixville, PA (US);

Michael A. Sturgess, Quakertown, PA (US);

Samala J. Rao, West Chester, PA (US);

Assignee:

Message Pharmaceuticals, Malvern, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention features compounds useful for inhibiting RNase P activity. These compounds can be used as therapeutics for treating or preventing a variety of bacterial infections. The compounds belong to several classes including mono- and bis-guanylhydrazones, guanylhydrazone mimetics, and benzothiazolium compounds. Exemplary compounds are compounds of formula I:Y—(NR')—U—(NR″)—A—(NR)—U—(NR)—Z  Iwith substituents as described herein.


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