The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2006

Filed:

Feb. 04, 2002
Applicants:

Takuya Shiraishi, Shizuoka, JP;

Shojiro Kadono, Shizuoka, JP;

Masayuki Haramura, Shizuoka, JP;

Haruhiko Sato, Shizuoka, JP;

Toshiro Kozono, Shizuoka, JP;

Takaki Koga, Shizuoka, JP;

Akihisa Sakamoto, Shizuoka, JP;

Inventors:

Takuya Shiraishi, Shizuoka, JP;

Shojiro Kadono, Shizuoka, JP;

Masayuki Haramura, Shizuoka, JP;

Haruhiko Sato, Shizuoka, JP;

Toshiro Kozono, Shizuoka, JP;

Takaki Koga, Shizuoka, JP;

Akihisa Sakamoto, Shizuoka, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/06 (2006.01); C07D 213/02 (2006.01); C07D 235/04 (2006.01); C07D 239/86 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound of Formula (1): wherein A crystal of a complex between factor VIIa/human soluble tissue factor and a low-molecular weight reversible factor VIIa inhibitor. A medium carrying a part or all of structure coordinate data of a complex between human factor VIIa/human soluble tissue factor and a low-molecular weight reversible factor VIIa inhibitor, obtainable by X-ray crystal structure analysis of the crystal. A method for computationally designing a low-molecular weight reversible factor VIIa inhibitor using the coordinate data.


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