The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2006

Filed:

Feb. 28, 2002
Applicants:

Robert A. Houtchens, Milford, MA (US);

Maria S. Gawryl, East Boston, MA (US);

William R. Light, Natick, MA (US);

Javed Baqai, Lexington, MA (US);

Inventors:

Robert A. Houtchens, Milford, MA (US);

Maria S. Gawryl, East Boston, MA (US);

William R. Light, Natick, MA (US);

Javed Baqai, Lexington, MA (US);

Assignee:

Biopure Corporation, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 1/02 (2006.01); A61K 38/16 (2006.01); A61K 35/14 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Red blood cells are purified by separating whole blood, such as by centrifugation, to form a red blood cell fraction and a liquid fraction. The whole blood can be defibrinated or treated to prevent coagulation prior to separation. Preferably, the whole blood is bovine blood. The red blood cell fraction is then diafiltered to purify the red blood cells. The purified red blood cells can then be lysed to form a lysate of purified red blood cells. The purified red blood cells and the lysate of purified red blood cells are suitable for use in producing hemoglobin blood substitute.


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