The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2006

Filed:

Jan. 02, 2002
Applicants:

David L. Hallahan, Wilmington, DE (US);

Natalie M. Keiper-hrynko, Bear, DE (US);

Inventors:

David L. Hallahan, Wilmington, DE (US);

Natalie M. Keiper-Hrynko, Bear, DE (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01); C12N 1/14 (2006.01); C12N 5/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The instant invention relates to bioproduction of isopentenyl diphosphate within the latex of the rubber tree,. Isopentenyl diphosphate (IPP) synthesis from acetate is mediated by a set of enzymes, acetyl-coA acetyltransferase, HMG-coA synthase, HMG-coA reductase, mevalonate kinase, phosphomevalonate kinase and mevalonate diphosphate decarboxylase, encoded by six genes isolated as expressed sequence tag (EST) cDNAs fromlatex. In addition, a variant sequence of one of these enzymes, acetyl-coA acetyltransferase, has been found.


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