The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2006
Filed:
Oct. 12, 2000
Peter H. St. George-hyslop, Toronto, CA;
Johanna M. Rommens, Toronto, CA;
Paul E. Fraser, Toronto, CA;
Peter H. St. George-Hyslop, Toronto, CA;
Johanna M. Rommens, Toronto, CA;
Paul E. Fraser, Toronto, CA;
The Hospital for Sick Children, Ontario, CA;
HSC Research and Development Limited Partnership, Ontario, CA;
The Governing Council of the University of Toronto, Ontario, CA;
Abstract
The present invention describes the identification, isolation, cloning, and determination of the Alzheimer Related Membrane Protein (ARMP) gene on chromosome 14 and a related gene, E5-1, on chromosome 1. Normal and mutant copies of both genes are presented. Transcripts and products of these genes are useful in detecting and diagnosing Alzheimer's disease, developing therapeutics for treatment of Alzheimer's disease, as well as the isolation and manufacture of the protein and the construction of transgenic animals expressing the mutant genes.