The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2006
Filed:
Nov. 18, 2003
Edgardo Laborde, Foster City, CA (US);
Louise Robinson, San Carlos, CA (US);
Fanying Meng, San Francisco, CA (US);
Brian T. Peterson, San Francisco, CA (US);
Hugo O. Villar, La Jolla, CA (US);
Steven E. Anuskiewicz, San Bruno, CA (US);
Yoshiro Ishiwata, Aichi-gun, JP;
Shoji Yokochi, Inabe-gun, JP;
Yukiharu Matsumoto, Gifu, JP;
Takuji Kakigami, Inabe-gun, JP;
Hideaki Inagaki, Anjoh, JP;
Takahito Jomori, Nagoya, JP;
Kouji Matsushima, Matsudo, JP;
Edgardo Laborde, Foster City, CA (US);
Louise Robinson, San Carlos, CA (US);
Fanying Meng, San Francisco, CA (US);
Brian T. Peterson, San Francisco, CA (US);
Hugo O. Villar, La Jolla, CA (US);
Steven E. Anuskiewicz, San Bruno, CA (US);
Yoshiro Ishiwata, Aichi-gun, JP;
Shoji Yokochi, Inabe-gun, JP;
Yukiharu Matsumoto, Gifu, JP;
Takuji Kakigami, Inabe-gun, JP;
Hideaki Inagaki, Anjoh, JP;
Takahito Jomori, Nagoya, JP;
Kouji Matsushima, Matsudo, JP;
Telik, Inc., Palo Alto, CA (US);
Sanwa Kagaku Kenkyusho Co. Ltd., Nagoya, JP;
Abstract
Chemical compounds which are antagonists of Monocyte Chemoattractant Protein-1 (MCP-1) function, pharmaceutical compositions comprising these compounds, methods of treatment employing these compounds and compositions, and processes for preparing these compounds. The compounds are useful in the prevention or treatment of chronic or acute inflammatory or autoimmune diseases, especially those associated with aberrant lymphocyte or monocyte accumulation such as arthritis, asthma, atherosclerosis, diabetic nephropathy, inflammatory bowel disease, Crohn's disease, multiple sclerosis, nephritis, pancreatitis, pulmonary fibrosis, psoriasis, restenosis, and transplant rejection.