The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2006

Filed:

Apr. 13, 2000
Applicants:

Bruce Edward Gerlitz, Indianapolis, IN (US);

Bryan Edward Jones, Carmel, IN (US);

David Thompson Berg, Beech Grove, IN (US);

Inventors:

Bruce Edward Gerlitz, Indianapolis, IN (US);

Bryan Edward Jones, Carmel, IN (US);

David Thompson Berg, Beech Grove, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); C12N 9/64 (2006.01); C12N 15/00 (2006.01); C12N 5/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel protein C derivatives are described. These polypeptides retain the biological activity of the wild-type human protein C with substantially longer half-lives in human blood. These polypeptides will require either less frequent administration and/or smaller dosage than wild-type human protein C in the treatment of vascular occlusive disorders, hypercoagulable states, thrombotic disorders and disease states predisposing to thrombosis.


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