The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2006
Filed:
May. 19, 1999
Applicants:
Maarten Nieboer, Delfgauw, NL;
Roelof Ary Lans Bovenberg, Rotterdam, NL;
Inventors:
Maarten Nieboer, Delfgauw, NL;
Roelof Ary Lans Bovenberg, Rotterdam, NL;
Assignee:
DSM IP Assets B.V., Te Heerlen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides DNA, heterologous host cells capable of transcribing, translating or expressing said DNA and methods employing such host cells and cultures thereof for an improved in vivo production of acylated cephalosporins with higher yield. According to the invention, a host cell is provided comprising an enzyme having expandase activity which is predominantly localized in the cytosol (as opposed to localized mainly in or with the peroxisomes or microbodies) of the host cell.